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Emerging risk factors collaboration diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies
Some important clinical considerations include: People with pre-existing diabetic retinopathy should be monitored closely, as rapid improvement in blood glucose control with semaglutide has been associated with temporary worsening of retinopathy complications [15] [16] GLP-1 receptor agonists may cause a modest increase in heart rate These medications should not be used in combination with DPP-4 inhibitors, as recommended by NICE NICE guidance recommends regular monitoring of HbA1c and body weight to assess treatment efficacy, with continuation of therapy dependent upon achieving meaningful clinical benefits within the first six months of treatment
Importantly, tirzepatide's effect on gastric emptying may affect the absorption of oral medications, including oral contraceptives
If you experience injection site reactions or notice the injection site turning red and itchy , rotate your injection site weekly
Safety issues of tirzepatide (pancreatitis and gallbladder or biliary disease): systematic review and meta-analysis
